Looking at Alternatives to Anti-Depressants

  • Post author:

I come across many clients (especially in the US), who are on some form of prescription medication. While you might imagine that this was prescribed for severe disorders, mostly it was for something less than that. I am of the strong opinion that if you are going through a difficult period, some amount of depression and anxiety are a natural consequence. This is often alleviated once that situation is worked through. How did we get to the to the situation where people are taking a huge number of tablets, half of which are to counter side effects (as I have seen frequently)?

Depression is a complex mental health condition that can cause a range of symptoms, including persistent sadness, feelings of hopelessness or worthlessness, loss of interest in activities, changes in appetite or sleep patterns, fatigue, difficulty concentrating, and thoughts of self-harm or suicide. Recent studies have raised concerns about the effectiveness of antidepressants as a treatment for it, particularly for mild to moderate depression.

Over the past few decades, there has been a significant increase in the prescription of anti-depressant medications globally. While these drugs can be somewhat effective for treating depression and other mental health conditions, there are concerns that they are being over-prescribed and used inappropriately, leading to massive profits for pharmaceutical companies, where the line between ethics and profit is a thin one. Have we become conditioned to believe that we need drugs for everything?

One reason for the over-prescription of anti-depressants is the medicalization of normal human emotions.

Many people experience sadness or anxiety at some point in their lives, and while these feelings can be distressing, they are a normal part of the human experience. However, in recent years, the pharmaceutical industry has marketed anti-depressants as a solution for anyone experiencing negative emotions, regardless of whether they meet the diagnostic criteria for a mental health disorder.

Another factor contributing to over-prescription is the lack of access to other forms of mental health care. Therapy, counseling, and other non-medical treatments can be effective for treating depression and other mental health conditions, but these services are often not covered by insurance or are too expensive for many people to afford. As a result, doctors may feel pressured to prescribe medication as the only available treatment option. There has also been evidence of doctors being encouraged to use medication over other treatments due to incentives offered by big Pharma, as was the proven case with OxyContin and Perdue Pharma. We can only hope this is an isolated case. However, my suspicion is that it isn’t.

It is important for doctors and patients alike to be aware of the potential risks and benefits of anti-depressant medications and to consider other treatment options when appropriate. By working to reduce the over-prescription of these drugs, governments can also help ensure that people with depression and other mental health conditions receive the most appropriate and effective care.

Anti-depressants can have serious side effects, and some studies have suggested that they may not be any more effective than placebo in treating mild to moderate depression. Furthermore, there is a risk of addiction and withdrawal symptoms with some anti-depressants, which can make it difficult for patients to stop taking them.

A study published in The Lancet in 2018 analyzed data from over 500 trials involving more than 100,000 participants and found that the difference in effectiveness between antidepressants and placebo was small for most patients. The study concluded that antidepressants were more effective for severe depression, but that their effectiveness for mild to moderate depression was questionable. Similarly, a study published in the journal Psychotherapy and Psychosomatics in 2021 found that only one in three patients who take antidepressants experience a clinically significant improvement in their symptoms.

Research from the University of London has also shed light on the role of serotonin in depression. While antidepressants are designed to increase serotonin levels in the brain, they may not be effective for all individuals with depression. Serotonin is a neurotransmitter that plays a key role in regulating mood, and reduced levels of serotonin have been linked to depression. However, recent research has called into question the idea that depression is solely caused by a serotonin deficiency.

A study published in the journal Neuroscience & Biobehavioral Reviews in 2020 analyzed data from over 50 years of research on serotonin and depression and found that there is no clear evidence to support the idea that depression is caused by a chemical imbalance or deficiency of serotonin. The study concluded that depression is likely a complex and multifaceted condition with many different underlying causes.

Similarly, a review of the literature published in the Journal of Affective Disorders in 2021 found that while antidepressants can increase serotonin levels in the brain, there is no conclusive evidence to suggest that this is the primary mechanism by which they alleviate depression. The review concluded that the relationship between serotonin and depression is complex and not fully understood.

This research challenges the idea that antidepressants are the only effective treatment for depression, and highlights the importance of exploring alternative treatments that may address the root causes of depression.

Psychotherapy, for example, has been shown to be effective in treating depression and helping individuals develop coping strategies. Mindfulness-based therapies and lifestyle changes like exercise and a healthy diet have also been shown to improve mood and overall well-being. Ultimately, it’s important for individuals with depression to work with a mental health professional to develop a personalized treatment plan that takes into account their unique needs and circumstances. While antidepressants can be a helpful tool in some cases, they are not the only option, and alternative treatments may be just as effective or more effective for some individuals.

Fortunately, there are many alternative treatments that can help alleviate symptoms of depression and improve overall well-being. Psychotherapy, for example, can help individuals work through the underlying causes of depression and develop coping strategies. Mindfulness-based therapies can also be effective, as can lifestyle changes like exercise and a healthy diet. Social support is also important, as it can provide a sense of belonging and purpose.

Mindfulness is a therapy which involves cultivating present-moment awareness and accepting one’s thoughts and feelings without judgment and is very effective for coping with depressive moods. This can be done through practices like meditation and yoga, and has been shown to reduce symptoms of depression and anxiety.

Lifestyle changes can also be helpful in managing depression symptoms. Exercise, for example, has been shown to improve mood and reduce symptoms of depression, while a healthy diet that includes plenty of fruits, vegetables, and whole grains can improve overall well-being.

Finally, social support is an important aspect of managing depression. This can include spending time with friends and family, joining a support group, or volunteering in the community. Social connections can provide a sense of belonging and purpose, which can help alleviate symptoms of depression.

While medication can be a helpful tool in treating depression, it is not the only option. By exploring alternative treatments like psychotherapy, mindfulness-based therapies, lifestyle changes, and social support, individuals can find a personalized approach to managing their depression symptoms and improving their overall well-being.

Ultimately, it’s important for individuals with depression to work with a mental health professional to find the best treatment approach for their unique needs. While antidepressants can be helpful for some individuals, there are alternatives. By exploring these alternative treatments and working to improve overall well-being, individuals can find hope and healing in the face of depression.


Dr. Nicholas Jenner, a therapist, coach, and speaker, has over 20 years of experience in the field of therapy and coaching. His specialty lies in treating codependency, a condition that is often characterized by a compulsive dependence on a partner, friend, or family member for emotional or psychological sustenance. Dr. Jenner's approach to treating codependency involves using Internal Family Systems (IFS) therapy, a treatment method that has gained widespread popularity in recent years. He identifies the underlying causes of codependent behavior by exploring his patients' internal "parts," or their different emotional states, to develop strategies to break free from it. Dr. Jenner has authored numerous works on the topic and offers online therapy services to assist individuals in developing healthy relationships and achieving emotional independence.

Leave a Reply

This site uses Akismet to reduce spam. Learn how your comment data is processed.

This Post Has One Comment

  1. Liz Keating

    Yes i agree with you 100 percent
    CBT therapy.Walks .
    Chat with a good trustworthy friend
    A phone call
    Much too quickly antidepressants are shoved in to peoples hands rather than asking people would they like to talk about their situations .
    And because of this then there is more problems added to their lives such as addiction .